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Developed, manufactured, and marketed by Zeneca Pharmaceuticals, ZOLADEX is an efficient and nicely-tolerated initial remedy used for the palliative remedy of advanced prostate cancer. Early-stage prostate cancer normally grows very slowly and should take years to cause any symptoms or different well being problems, if it ever does in any respect.
21 , 22 Two giant multinational phase III trials in men with metastatic CRPC demonstrated improved total survival over placebo in both prechemotherapy (PREVAIL A Security and Efficacy Study of Oral MDV3100 in Chemotherapy-Naive Sufferers With Progressive Metastatic Prostate Cancer 4 ) and postchemotherapy (AFFIRM Security and Efficacy Study of MDV3100 in Sufferers With Castration-Resistant Prostate Cancer Who Have Been Beforehand Handled With Docetaxel-based mostly Chemotherapy 3 ) settings.
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